Pleural Fluid and Histologic Analysis

نویسنده

  • Steven A. Sahn
چکیده

Although talc slurry pleurodesis is effective for control of malignant pleural effusions and recurrent pneumothorax, the mechanisms of pleurodesis remain incompletely defined. We instilled 70 mg/kg of sterile asbestos-free talc slurry into the pleural space of New Zealand white rabbits and studied the inflammatory response at 1, 2, 3, 7, 15, 30, 60, 90, and 120 days by observing pleural fluid and histologic characteristics. Talc slurry caused mesothelial denudement and an exudative neutrophilic pleural effusion that resolved after 48 h. A transient mononuclear vasculitis was seen within the

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تاریخ انتشار 2007